Weepi

Improving management of non-AIDS comorbidities among people living with HIV in Georgia

Grantee

Infectious Diseases, AIDS and Clinical Immunology Research Center (IDACIRC), Georgia

Main applicant and principal investigator

Prof. Tengiz Tsertsvadze, Director General, IDACIRC

Deputy applicant

Pati Gabunia, Head of HIB inpatient department, IDACIRC

Background

Increasing life-expectancy of people living with HIV (PLHIV) is accompanied by increases in the prevalence of non-AIDS comorbidities (NACM). Georgia has made significant accomplishments in effective delivery of HIV treatment and care. Patterns of cause-specific mortality has been changing following universal availability of HIV antiretroviral therapy (ART), with more persons dying from non-AIDS than AIDS related causes. However, little is known about the burden of NACM in Georgia. The existing HIV care model has primarily focused on ART provision and management of infectious complications of HIV. Management of NACM has not been integrated in national guidelines. It is therefore critically important to better understand the magnitude of the problem and develop an appropriate care model to effectively tackle the expected impact of NACM on clinical outcomes.

Objective

This study will assess the prevalence of non-AIDS co-morbidities among HIV patients in Georgia, aiming to improve the management of NACM, particularly cardiovascular disease (CVD), chronic kidney disease (CKD) and diabetes mellitus (DM), and aiming to integrate management of NACM into national guidelines.

Methods

The study will enroll 1,200 HIV patients to estimate prevalence of CVD, CKD, DM and dyslipidemia. The study will be based on routinely available data from medical records supplemented by a patient survey. Latest EACS recommendations on managing NACM will be implemented and the actual service delivery will be assessed by auditing medical records.

Output / impact

The study findings will be widely disseminated and used to advocate for policy changes related to the management of NACM. Partnerships with national and international experts will be established to support sustainability.